5-Bromo-2-furancarboxylic Acid Ethyl Ester
ethyl 5-bromofuran-2-carboxylate
CAS: 6132-37-2
Molecular Formula: C7H7BrO3
5-Bromo-2-furancarboxylic Acid Ethyl Ester - Names and Identifiers
| Name | ethyl 5-bromofuran-2-carboxylate |
| Synonyms | Ethyl 5-broMo-2-furoate ethyl 5-bromofuran-2-carboxylate ethyl 5-bromo-2-furancarboxylate ethyl 5-broMo-2-furancarboxylate Ethyl 5-bromofuran-2-carboxylate 5-Bromo-2-furancarboxylic Acid Ethyl Ester 2-Furancarboxylic acid, 5-broMo-, ethyl ester |
| CAS | 6132-37-2 |
| InChI | InChI=1/C7H7BrO3/c1-2-10-7(9)5-3-4-6(8)11-5/h3-4H,2H2,1H3 |
5-Bromo-2-furancarboxylic Acid Ethyl Ester - Physico-chemical Properties
| Molecular Formula | C7H7BrO3 |
| Molar Mass | 219.03 |
| Density | 1.533±0.06 g/cm3(Predicted) |
| Melting Point | 17 °C |
| Boling Point | 234 °C |
| Flash Point | 100.9°C |
| Vapor Presure | 0.0325mmHg at 25°C |
| Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
| Refractive Index | 1.52 |
5-Bromo-2-furancarboxylic Acid Ethyl Ester - Introduction
Ethyl 5-bromofuran-2-carboxylate, chemical formula C7H7BrO3, is an organic compound. The following describes its nature, use, preparation and safety information:
Nature:
-Appearance: Ethyl 5-bromofuran-2-carboxylate is a colorless to pale yellow liquid.
-Melting point:-36°C.
-Boiling point: 158-160°C.
-Solubility: Soluble in organic solvents such as ethanol and ether, difficult to dissolve in water.
Use:
-Ethyl 5-bromofuran-2-carboxylate is an important organic synthesis intermediate, widely used in the synthesis of drugs, pesticides and other organic compounds.
-It can be used to synthesize biologically active compounds, such as antiviral, antitumor and antibacterial agents.
Preparation Method:
- ethyl 5-bromofuran-2-carboxylate can be obtained by reacting ethyl furan-2-carboxylate with bromide.
-The specific preparation method is to react ethyl furan-2-formate with the nucleophilic reagent sodium bromide or 2-bromohydrated alcohol in an inert atmosphere, and react in an appropriate solvent to obtain ethyl 5-bromofuan-2-carboxylate.
Safety Information:
-Ethyl 5-bromofuran-2-carboxylate exposure and inhalation may cause health hazards, and long-term or large-scale exposure should be avoided.
-Wear appropriate personal protective equipment such as goggles, protective gloves and protective clothing during operation.
-Avoid contact with skin, eyes and respiratory tract. If contact occurs, rinse the corresponding area with plenty of water immediately and seek medical help.
-Waste shall be disposed of in accordance with local regulations and shall not be discharged directly into the natural environment.
Nature:
-Appearance: Ethyl 5-bromofuran-2-carboxylate is a colorless to pale yellow liquid.
-Melting point:-36°C.
-Boiling point: 158-160°C.
-Solubility: Soluble in organic solvents such as ethanol and ether, difficult to dissolve in water.
Use:
-Ethyl 5-bromofuran-2-carboxylate is an important organic synthesis intermediate, widely used in the synthesis of drugs, pesticides and other organic compounds.
-It can be used to synthesize biologically active compounds, such as antiviral, antitumor and antibacterial agents.
Preparation Method:
- ethyl 5-bromofuran-2-carboxylate can be obtained by reacting ethyl furan-2-carboxylate with bromide.
-The specific preparation method is to react ethyl furan-2-formate with the nucleophilic reagent sodium bromide or 2-bromohydrated alcohol in an inert atmosphere, and react in an appropriate solvent to obtain ethyl 5-bromofuan-2-carboxylate.
Safety Information:
-Ethyl 5-bromofuran-2-carboxylate exposure and inhalation may cause health hazards, and long-term or large-scale exposure should be avoided.
-Wear appropriate personal protective equipment such as goggles, protective gloves and protective clothing during operation.
-Avoid contact with skin, eyes and respiratory tract. If contact occurs, rinse the corresponding area with plenty of water immediately and seek medical help.
-Waste shall be disposed of in accordance with local regulations and shall not be discharged directly into the natural environment.
Last Update：2024-04-09 15:17:58
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CAS: 6132-37-2
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CAS: 6132-37-2
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